A Murine Model for Disseminated Candidiasis in Neonates
نویسندگان
چکیده
منابع مشابه
Isavuconazole pharmacodynamic target determination for Candida species in an in vivo murine disseminated candidiasis model.
Pharmacodynamic (PD) studies with triazoles in the neutropenic murine disseminated candidiasis model have been performed extensively for Candida albicans. They have consistently shown that the pharmacodynamic index most closely correlated with efficacy is the ratio of the 24-h area under the concentration-time curve (AUC) to the MIC, and a target 24-h free-drug AUC/MIC ratio near 25 is associat...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 2011
ISSN: 0031-3998,1530-0447
DOI: 10.1203/pdr.0b013e318206fd3e